When Frontline first came out (many many years ago), my vet was very enthusiastic about the product - I remember him distinctly saying how safe it was, and how you could rub all over your body, even wash your hands in it, without risk.

I've never rubbed it all over my body or washed my hands with it, but I have used it on my dogs for years, and it works great. Better than great. It's a great product.

Justin