Easy, Hook up the fully loaded pop-up camper to the truck and the always loaded quad/bike trailer to my wifes AWD van and go. There is always 50 gals of stabilized gas on the bike trailer, even with todays prices we don't let our vehicles get below a 1/2 tank. We both carry two cases of 1 litre bottles of water in our vehicles. The only things that would need to be loaded are guns and ammo. We'll have food, medical supplies including perscription meds, tents and tarps tools including a chainsaw, extra clothes for the whole family (bought cheap at goodwill and easy to rotate without a lot of expense), 50 watt solar panels, communications and most comforts of home.
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What you know isn't as important as knowing what you don't know