>> A 200 grain Speer hollowpoint (the old style with the enormous cavity) would be my choice and at 25 feet I'm betting it would only take one. <<

The very one! And launched at a fair bit over 1,000fps (+P+ and not for a poorly ramped gun) , you can readily get the job done quite a bit farther away - if you can hit the zone, it will do the job as nicely as anything. Nyah-nyah - I have a LOT more than 1/2 box left..

My current fav, though, is the Remington Golden Saber stuff - I no longer feel an urge to reload "for business" with those readily available. Haven't tried them, but the Federal Hydra-Shok has a huge real-world reputation that continues, despite being the oldest of that "new" generation of performance pistol ammo.

Run a few clips of the Golden Sabers thru your M1911 and see what you think...