In my opinion the tradeoff looks like this:

InReach allows for a lot more communications options and has a proven privately-operated Rescue Coordination Center (RCC). There’s a subscription cost. I think all the modern units are USB rechargeable, with the tradeoffs inherent in that.

PLBs have no communications options other than “help” and have the world standard for RCC (USCG or USAF). There is no subscription. They are certified to work for a given number of years and then need an expensive factory service to replace the battery.

I still am considering buying an InReach for the admittedly rare times that I’m both off the beaten track and don’t have an easier to use comms option. I would buy a PLB if I were going to do something truly adventurous, and probably keep it on my person at all times.