Montanero wrote:
> What kills is penetrating through something vital and causing > enough damage. So large and fast would be good.

Sounds logical. But you could also say the smaller the bullet, the deeper it is going to penetrate, increasing the chances of hitting something vital.
As I said: the laws of physics are a bit hard to argue with. That much energy is hitting the baddie, whatever shape the bullet is.
And the proof is in the pudding. With the possible exception of the .400 Corbon, all those calibres are used by many police. I'm sure we'd be hearing from officers who were being gunned down while their bullets were not dropping the baddies, if some didn't work.
There doesn't seem to be that much difference in reality.