Interesting thread and some good ideas.

Here is my culled take on it based on all the suggestions and also based on my urban GHB which is designed for this same scenario.

Note that I listed all the suggestions into one big list that originated with Dagny's. For clarity and brevity, I removed most of the duplicate suggested items and original accompanying comments then added my comments. Feel free to counter comment

Any items and comments I added are in blue.

Portland map - Paper map is the best idea. No need to worry about a cellphone battery dying or other post quake communication problems.

Button compass - Not needed. I have been to Portland a few times with last being in 2009. I found Portland an easy city to find my way around in. Depending on weather, Mt. Hood will give a good indication of direction. Also with the Columbia River to the north and the Willamette River separting downtown Portland to the west and with Highway 5 along with 99 running east/west, I cannot see how anyone who has lived there any length of time, could get that lost. Also in the aftermath of the 2011 Japan earthquake, I recall seeing on the news, entire blocks of houses and buildings destroyed but there were still plenty of traffic direction and road/street signs that were untouched. I would suspect the same happens in any quake anywhere.

AM-FM radio + extra AA batteries - Great idea. Keep in mind that any local radio station will probably be off the air and people will have to rely on distant stations and as in all disaster events, the initial news and reports is sketchy at best.

FIRST-AID
Adventure Medical “Wound-Care” kit
assorted large bandages, non-stick pads, gauze, tape
sanitary napkins (4)
eyedrops/wash
meds (ibuprofen, aspirin, benadryl)
Foot powder- As the sister may be walking 10-14 miles, a small plastic bottle of foot powder is a good addition, especially for those who may encounter hot spots on their feet from walking/moisture etc. The bottle I have is about 2 inches high by 3/4/ wide and deep.

LIGHT
Petzl e-lite headlamp
Fenix E-20 (uses one AA battery) + extra battery

WATER
32 oz Nalgene canteen
Rothco canteen carrying pouch
Micropur tablets
Collapsible water bottle - Depending on time of year, 32 oz of water is not a lot for somone who maybe on foot for 12-24 hours. The problem with adding on more water is that it is heavy and bulky. We could assume that the sister would be at the hospital when the quake happens and maybe able to get some more water before pressure is lost completely or the hospital has a backup water system or stored bottle water. Even so, I would add a collapsible water bottle to the kit. These bottles weigh next to nothing and when folded, take up no room.

FOOD
energy bars (2)- Not enough for someone who maybe walking in some possible adverse conditions like winter cold and rain for 12-14 hours.
Mixed nuts - Ensure your body is used to these. I cannot eat mixed nuts without a long term and short intake introduction to them otherwise I get the worst gut aches.

hard candies - I initially wanted to say skip these as there is there is only the sugar to give you a quick boost of energy but that energy will come crashing down just as fast as the sugar high wears off. However a handful of hard candies may give a bit of a moral boost so leave them in the kit.

FIRE
BIC lighter (wrapped in hot pink duct tape)
REI Stormproof matches
mini-firesteel, scraper & cotton balls & Vaseline lip/skin balm (petroleum jelly) - Scrap the firesteel, there are already matches and lighters for firestarting. Also if someone is not versed in lighting fires with a firesteel, it could be a futile effort in terms of time, energy and frustration wise.
tea-light candle- Ditch it. Instead include a votive style candle or a 6" inch sized. Either one, wrap in plastic wrap to keep clean.

TOOLS
fixed blade knife (Morakniv)
mini pry-bar - Stanley 7-1/2-Inch model is the best balance between size/weight and usefulness.
gas & water shut-off -Cannot think where an inexperienced person would ever attempt to shutoff gas. Also if they did, the shutoff tool needs to be brass, aluminum etc so it will create any sparks if it comes into contact with steel gas pipe.

seatbelt cutter - Not needed if the person has the above knife.
mini-Leatherman - Already have a knife, a small set of standalone pliers or better yet, a 5" size vice grip is infinitely more versatile then the pliers on the Leatherman. Of all other tools on the Leatherman, what use in this scenario would they have.
first-aid scissors - Debatable. Already have a knife that will cut any fabric.

WARMTH
chemical hand-warmers (4)
AMK Heatsheet
garbage bags (2) -- makeshift poncho
Blue foam bum pad - By far, one of the best - if not the best outdoors related product I have ever purchased. These thin and very lightweight pads have so many uses other then their original purpose. They can be placed into the back or back of a jacket to block wind and help warm the body. Used in the front of a backpack to keep pointy objects from protruding into your back. Used as is as a roll up splint for a broken leg or can be cut up for a broken arm splint - I have personally seen this in a mountain rescue. Used to help fan a stubborn fire to catch and much more.

MISC
Kleenex packets (2) - Ditch it. For more versatility, add some folded paper towels into a zip lock bag. The paper towels do not need to be the real thick type as the thinner types fold and pack better.
Storm whistle
N-95 mask
bandannas (2)
hiking pole - Debatable depending on route and area of Portland. Also the earthquake will bring down a lot of trees. Pretty easy to snap off a small branch and improvise a walking stick.

550 paracord
work gloves
moleskine notebook + pen + Sharpie
cash ($20 in ones) - Add at least 3x that much.


Phone charger, hopefully for her smartphone that has local topo maps on it - Yes for the phone charger but keep in mind cell service maybe completely non-existent for days/weeks. See above in regards to phone vs maps for route finding.

First aid materials for feet (I recently became a big fan of the Foot Care Module from Rescue Essentials, no affiliation) - Best first aid for the feet is to keep them in walking condition. I keep active enough but the rare time as happened earlier this year, I got heal blisters real bad (to the point of almost crippling me) from a pair of hiking shoes that in years past, never bothered me. Since then, one of main goals is to keep my feet as toughened as possible. I am no Cody Lundin when it comes to walking barefoot outdoors but I am now to the point where walking on rough ground and gravel has calloused my feet enough that blisters are no longer a concern. I don't expect anyone else to do this but regular distance walking in your planned GH shoes is recommended.

Spare pair of well broken-in boots - A good pair of running shoes or lighweight hiking shoes is much better option. Heavy boots makes for a lot extra expended enenery . See this thread [color:#3366FF]http://forums.equipped.org/ubbthreads.php?ubb=showflat&&Number=205727 from about 5 years ago, especially my post in regards to boot weight and energy expended over miles walked.[/color]

A full-size Leatherman - IMO, not needed. See above for reasoning.
Rain poncho or jacket - as in the list above, garbage bags can be a makeshift option.
A warm fleece - Depends on time of year. if the weather is cool enough for a fleece, chances are sister is wearing as weater or jacket to work already. Also the fleece adds bulk to a GHB.
Signal mirror - Not needed in an urban environment.
Spare glasses if she wears them
Dry clothes to wear, most especially socks - Debatable on the dry clothing unless it lightweight synthetic which usually takes less room then the cotton equivalent. Keep in mind, the sister may only walking 10-14 miles which for someone in average condition is very doable in a long day depending on detours etc. One extra pair of synthetic athletics socks is idea.
Spare sunglasses - Why? I can see having to have spare prescription glasses though.

On-Duty 6 in 1 Tool. Channel Lock 6 In 1 Model 88, 9" , HD , plier, cutter, pry bar , water/ gas shutoff and spanner wrench - Big, and heavy (almost 1 lb.) Is the average person going to know how to safely shutoff gas etc.

4 way Silcock wrench/tool - Single use tool. 5" Vice Grips mentioned above will open any Silcock equipped water pipe. Also vice grips have far more uses beyond this.

Small package of antibacterial wipes for wound & personal hygiene. - Watch which kind of wipes and where you wipe, especially for women. Ask my wife how she found out the painful way.

A gimmicky Stansport shovel, axe & saw, lightweight tool. - Not something I would include in my GHB bag due to size / weight and impractical use if my goal is to get home.


Red Ledge Thunderlight jacket, in High Vis Orange.

Pair of leather work gloves. Full on work gloves are bit bulky, however there are some smaller versions which have a leather palm section but the top and cuff are medium cotton. I use these type all the time for camping, gardening, wood chopping, tree clearing etc.

Metal cup to boil water - Not needed in an urban GHB.

Add in salty simple carbohydrates (i.e. pretzels) for on the move energy. - Energy bars would be a better option.

MISC:
Duct tape (gear repair - like shoes)
Pocket hone - Ditch it. Sister is interested in getting home in 12-14 hours. Any actual knife work required where the blade would rapidly dull would probably be minimal. Also probably does not know how to properly sharpen a knife anyway?