Absolutely. Christmas Eve 2004 knife slipped while opening thick clam shell packaging.

Slice.

Close & drop knife.

Grip thumb with other hand

"Grab your keys & pocketbook, we're going to ER."

One look, grab paper towel & deathgrip on thumb with other hand.

Next time I let go was at the ER triage station.

I've figured out that stuff is safer opened with a knife cutting toward your body. Brace it between one hand and your chest and cut away from your hand (yes, this is toward your body). Holding the knife in a full fist grip means even if it slips you get at most a minor cut. Your thumb on the hand holding the knife will hit your chest before the blade.

I've been cut with both dull & sharp knives. Sharp hurts less & heals faster.