I'm partial to full-grain leather because it goes better with my business attire. This has been my daily carry manbag for essentials that are always on my person, even while walking around the office:

Ebay - Leather Manbag

Walking around the office with some sort of nylon waist pack would look too weird. I also carry a briefcase for my laptop and papers.
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If you're reading this, it's too late.