while more powerful and having better bullet design options, if deer (or defense) is the goal, then 22mag is far from the ideal choice anyway.

22mag is far more expensive, harder to find, louder and does more damage on small game.

22LR is cheaper, will always be easier to find, allows for lots more practice for equal cost, and much much quieter (particularly with subsonics in a rifle).

but like any cartridge, they should both always be used within their capability, ie: small game.