From the other thread, now moved here:
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Originally Posted By: Montanero
And a .410 will not knock down anything large. Good for birds and squirrels, but not deer.

While deer CAN be taken with .410 slugs (it's legal in some states, illegal in others), I would consider it only in a survival situation, for someone who is experienced with their firearm, is a good shot, and knows where to place the shot. .410's are generally used by either: 1) experts, or 2) children and recoil sensitive adults.