It's not just the drug, it's the delivery agent as well. A petroleum-based delivery agent may be just fine for your skin, but not so good for your eyes.
Oh goodness, I would never recommend using regular Neosporin in your eyes! But the OP was questioning whether the opthalmic version could be used on general wounds. I'm assuming that the OP finds the small packaging of the opthalmic version to be convenient for him and that's why he's asking.
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