All in all, no no hassles at all, exceptin in Washington DC, where we got some static, but were not denied entry because of my rescue knife.

But I don't make a big show of it - it's just a small black bag that I carry all the time, you know? Most people only see the outside of it, and maybe I pull the first aid kit out. I don't have to explain why there's an MRE, KI tabs and various tools and such, since I don't go around dumping out my kit on the table all the time.
On the other hand, people who know me and hang out with my will casually ask me things like, "Say, do you have some electrical tape, glow sticks and zip-lock bags I could use?" and expect me to have it nearby.

And in all seriousness, my EDK is really that - I use something out of it almost every day, just running round being dad, a fireman, the guy at my son's school who fixes stuff and a homeowner.