I don't like Glocks, but that is primarily due to the grip angle. I started shooting a 1911 when I was about 12, and never stopped. Carried a S&W 4006 on duty for ten years or so, and liked that, 'cuz the grip angle is about the same as the 1911. My Kahr MK-40 the same. Glock is (or at least feels like to me) about 90 degrees off of the 1911/S&W, so I just can't point shoot it (a very important thing to me) worth a damn. Plus, the trigger, for some reason, beats a hole in the tip of my trigger finger. Don't know why, but it does. But many people love the plastic monsters. If you do not have the muscle memory of a completely different grip angle, you shouldn't have a problem...
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OBG