I have used a few different bags from Crumpler for computers and cameras and have found that they hold up very well and do not generally look like computer or camera bags.
Their site is a little goofy but the products are great:
http://www.crumplerbags.comI currently haul my computer and a basic camera around in their Customary Barge which also lets me pack a camera and a couple of lenses and looks like a basic book pack. The padded camera case can be removed to provide a lot of extra storage.
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