Regarding your ulcerated leg wound: there are always a lot of questions to ask to determine if you are receiving the best care but from my past experience, two are critical?

1 If you are getting home health care, do they really know what they are doing? I have some bad experiences with some home health care workers. Some of them simply lacked appropriate training and experience.
2. Can you get a second opinion and possibly a more aggressive alternate treatment plan inspite of the various changes in antibiotic therapy? One wound regranulation therapy I have witnessed was a "wound pump". A seal is placed over the wound and the pump is connected to it. It itermittently creates suction and pulls blood to the surface and develops cell granulation more efficiently and helps to remove drainage. It speeds up healing from months to a few weeks. It may not be the therapy for you, but just a thought or other avenue to explore.

Best of luck to you and best wishes.