Arrogance does seem to have a role in his decision making. He put his wants above the health needs of many/any others. You can make an argument that his travels up until he was notified of the severe TB strain was okay because he wasn't in a contagious stage. . .I wouldn't make that argument. Once the XDR TB strain was identified however, he was obligated to comply with CDC and do whatever he could to minimize the spread of the strain -- he didn't.

That said, whoever told him to turn himself in to the Italian health establishment was an idiot. They should have had the paperwork to take him into custody in Rome and transport his ass back to the U.S. ensuring further spread of the disease was minimized. The interview indicated that option was there; it shouldn't have been an option, it should have been Plan A.

Hopefully, his low risk of being contagious will give us a pass, but as a practice run I'd have to say that patient zero acted very typically and the CDC didn't do enough to contain the problem.