Jim, you keep defending items on thier volumes, but you origionally asked how to drop the mass.

I would probably loose the saline and irrigate with potable water, but you also have (no offense) a FAK fetish. :P I saw you were going to take the opinel and keep the mora; I'd do it the other way, but that's just me.

I think the biggest thing is, this kit needs to decide what it is. Is it a mini-BOB? Is it an oversized PSK? Is it an overnight camping pack? It could be all of these, but it doesn't feel like it is any of them yet. If a mini-BOB, I'd be expecting to see rain gear and thermal layers. If an overnighter, more in the way of shelter. And if a oversized PSK, your FAK is big bordering on paranoid- again, no offense intended, but it is possible to be TOO prepared. And based on what you've told us about your area, I would try to turn this more into a mini-BOB. And if the pack doesn't fit, you need a new pack- don't get wedded to BOB's skin.