When I am on the road I am always on my own. At some point in this scenerio (scince you said regionally) people are gonna want to start leaving the area. you have to wonder if any measures will be enacted to prevent the spread to unaffected areas, then common sense says if they don't let people out then no travel (including truck drivers) will be let into the area. Everything will come down to what plans individuals, towns, counties, states and the U.S. goverment have in place prior to the beginning. Basically without PPP (Prior Proper Planning) this scenario has no good out come, and I have never seen evidence of PPP on any large scale it's gonna be bad.
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Depend on yourself, help those who are not able, and teach those that are.