I've been through two stages of it. The first one was accompanied by a serious period of clinical depression. After hospitalization, treatment and newer forms of medication I found life to be an amazing experience again.

My second experience was in the late 90's when I realized that my career choice had been a poor one (money doesn't equate to happiness). After going back to school, completing a graduate degree in a academic field that I loved, I became a high school teacher. The intangible benefits of helping teenagers grow up to be responsible adults outweighs any salary for me. My wife and I got off the fast track, found a simpler life and never have looked back.