It varies depending on where I'm going but the things that are always in it are:
2 knives ( my larger knife and a small pocket knife)
cell phone
phone numbers ( small laminated card)
roll of quarters
about $50.00 In small bills and stashed in different places
ID
credit card and check book
small first aid kit
compact with mirror and magnifying glass
film canister with 3 fish hooks , 3 sinkers, about 20' of 8# spiderwire.
a small sewing kit
energy bar
small bottle of water
small pill box with tylonol and asprin
small spool of artificial sinue
whistle
2 bic lighters and 1 box of matches
small leatherman tool
a bandana
a gallon sized baggie
a couple of paper clips and rubber bands
tube of super glue
because make- up is heat sensitive , I dont carry it in my purse so that leaves lots of room for other things and it's not as heavy as you would think, or maybe I'm just used to it.

I keep my EDC bag strapped into the passenger seat so if I have the fortune to be able to get myself out of my car in an accident, I'll at least know where my gear is. Although I don't have a good alternative if someone is riding with me...

One thing we need to remember is, "can I access my emergency escape tools if I'm upside down with gravity working against me?" An accident would be disorienting to say the least, so it also has to be easy enough to use and find when you're not at 100% mental sharpness.

And practicing acessing these things is very important. In an accident we may be relying on instinct and muscle memory to get us out. I think of it like tying knots...you may be able to tie a knot while camping on a nice day or while sitting in your living room, but do you know the knot well enough to tie it with nasty wounds, exhausted with numb fingers and knowing if you can't tie the knot to secure your shelter you very well may die? As I have said many times before, if you have to think about it, you don't know it well enough. I may have to add that to my sig line...

I would add a poncho, duct-tape,chap stick and some tinder