I tried the Duragesic derm for a while. I finally gave up on it because I could never get it to stay on. I even tried glueing it on with spirit gum. This stuff is supposed to be used for theatrical attachments. That worked better, but still not good enough. Even when on, it tended to bulge up in the middle, causing the membrane to partially lift, impairing the transfer of the med to the skin. I would like to try Mastisol (skin adhesive), but it is expensive.