I have also trained with jamming my hand between the hammer and firing pin. Such moves aren't pleasant, but a blood blister or shredded palm is nothing compared to a bullet.

But to the point of the original post: if you have an assailant within arm's reach of you and you have your weapon drawn, unable to move in any direction, you should demand that they back away outside of your reach. If they refuse and/or tense for an attack (there are many tells for this) they have just taken a job as a hot lead catcher. Start firing and don't stop until they do. Obviously, being aware that this slide removal *might* be possible in extremely rare circumstances, you have forknowledge to not let your assailant get that close. Check your local laws for legality of said defensive strategy - IANAL.

FWIW I also own this fine piece of weaponry. Don't let someone tell you it's not a worthy gun. The JMH home defense ammo is pretty nasty (even if it's not a .40 or .45). Practicing against a vice or other non-moving target (you) is NOTHING like doing it to someone who's trying to avoid and squeeze off a round. I'd like to meet the person who can pull off my rail as fast as I can pull the trigger. This is one for movies and bar bets. Oh, and the 92FS is a pig - it eats everything I feed it... it just keeps firing round after round and never ever jams.