Use the ammunition that is most reliable in your pistol (proper feeding and ejection and absence of misfires).

Strongly disagreeing with another post: DON'T plan on head shots. That is an unreliable caliber on human skulls; there is over 100 years strong evidence of this. And the brain on a moving person is a small and evasive target to boot. Practice for multiple torso hits, preferably in the vicinity of the heart.

The "insurance" shot for this caliber has always been reported to be a single round in the heart at point blank range. I suspect, but do not know, that abdominal hits can be disuasive, but they are probably not an immediate deterent.