A major downside to the use of NSAIDS has been stomach complaints including ulcers. I have been using them (mainly Daypro) for 16 years for a back condition with little trouble. Shortly after I started using them, my prescriptions shifted from the orthopedist to my very wise family physician, luckily an internist, who provided regular family care. He prescribed the equivalent of Tagamet or Zantac one hour before taking the NSAID. It seems to help me a lot. I always carry a supply of a few pills. YMMV.

John