If there ever is a time you want to be operating @ 100% disasters is it. I would not want to take anything that would alter my mental balance in any way. A person’s brain is made to send danger signals, warnings and pain information to keep abreast of your surroundings. For me this is not theory but a chose I have made in the past. I have gone with out pain medications because I wanted to have 100% mental function, I can always quit hurting later when being less than 100% will not endanger myself or others around me.