Personally, I think non-lethal (less lethal) ammunition is a bad idea in general for personal self defense.

Consider:

If you only load your firearm with less lethal ammunition, why use a firearm at all? Perhaps a Taser like the X26 might be a better selection.

Less lethal ammunition probably is pretty lethal in close quarters.

If you use both normal amunition and less lethal ammunition you likely:

1) won't have what you need loaded and
2) you are likely to screw up.

-john