You would probably have to have the slide custom-milled and refinished. Alternatively, there are picatinny rail mounted gizmos like this (
https://www.amazon.com/Mako-Universal-Picatinny-Mount-Pistols/dp/B004O6CDV0) that can provide you a place to install a red dot sight. However, it may be very difficult to find a holster that would fit a pistol with one of those. I’d also wonder how well it would hold zero.