What does time have to do with it? The insulation moderates the outside temperature reaching the contents, whether hot or cold. You would need to access and check the contents regularly anyway, as you would with most important pieces of gear or supplies. You can get a better cooler, with better insulation, or you can store in your car with no insulation, your choice. You pick which one is better. To insulate or to not insulate, that is the question.
Insulation will only slow the warming. Left in a hot car long enough, the contents of an insulated first aid kit will eventually warm up to the ambient temperature inside the car.
If you don't believe me, try a simple experiment. Take an insulated cooler, and fill it with icy cold cans of beer. During a heat wave, put the cooler inside a locked car, parked in the hot sun. A day or two later, drink your now warm beer. Better insulation will buy you more time, but given enough time the end result is always the same. The temperature inside the insulation will reach equilibrium with the temperature outside the insulation.
This is a consequence of the Second Law of Thermodynamics. Physics always wins, in the end.
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