From my perspective....Antibiotics....
Most important is hygiene. Hand washing. IF it got to the TEOTWAWKI situation....then yes I'd use the antibiotics... that being said.... there are 'specific' antibiotics for specific infections.... certain bugs respond to certain antibiotics better than others. Assuming you don't know what the bug is, a broad spectrum antibiotic would be a good start. The docs I come across on a daily basis would tell you that getting a more specific med for the specific bug is better. But most of the docs I 'know'don't like jumping to antibiotics.
As for the 'prevention' aspect..... I'd say don't. Better minds may have good reason otherwise but personally.... there is a reason we are seeing MDROs (Multiple Drug Resistant Organisms). TOO MUCH antibiotic drug use! Too many 'super bugs' are out there.
A biochemist friend of my wife and my wife agree.... what will 'bring us down' is going to be something like these super bugs.