I have the LAPG Bail Out Bag. While it offers a great deal of organization, it is also heavy for its size and not very big for the number of compartments it has. I'd think of it as a giant pocket organizer. It's best for bugging out in a car and for organizing the relatively small items that you need quick access to. Some people use it as a range bag.
Walking for a long time or carrying bulking items -- ye olde backpack works far better.