I've seen reports that with Trail Boss powder (for handguns), you can get by with just filling the case. I certainly haven't tried that personally! I use and like Trail Boss, but I measure it, per standard reloading practice. And measured amounts don't fill the case most of the time. But they do take up significantly more case volume than other powders, sometimes to the point of almost filling the case in some calibers.

If I had to pick one handgun powder to use for everything, and wouldn't be allowed to keep anything else on hand, it would be W231. That one works with all the handgun cartridges I reload (but don't fill the case with it!)