Quite possibly, you may even understate the volatility of the emotional politics that surround wolves. However, Isle Royale presents an ideal laboratory situation - no hunting and minimal human presence (effectively none during the winter months and not that many during the rest of the year). From a cursory reading of the reference I cited, it would seem likely that both climate change and wolf predation, among other factors, could effect moose populations...

I am not a wildlife biologist not have I played one on TV....