Well, it wasn't until a couple of years ago that I started to think about gear and handed-ness. I am a lefty by birth, but was scolded early in childhood about writing with my left hand ("only stupid children write with their left" my teacher tried to tell me) and started at an early age to use both. I play sports right handed, but do most everything else left. I would have to say that my dexterity with the right is about 80% of the left, and I can write with the right hand at about 60% of the left. Of course, being a lefty that isn't saying much since we lefties are notorious for having bad handwriting. Anyway, back to the subject, I have found that most items are ambidexterous. With the exception of some scissors and golf clubs. When I bought my CRK Sebenza, I thought seriously about getting a left hand model since I usually handle the knife with the left, but decided it wasn't that big of a deal, and I got a great price on my right handed version.