Fortunately, I'm the type of guy that wears regular white cotton crew socks on a hike and have no problems. A week long backpack might net 1-2.
I am in the same boat. I have worn white cotton crew socks for years. I used to run a lot of miles many, many years ago in the orbiters. Never had a problem. I have heard of others whose feet would be like someone ran them over a cheese grater. Never figured it out.