I went to a 2wd truck for many reasons other do, never needed 4x4, got along fine with a locking rear end and chains. But then ran across one occasion where I did need it, my 2wdmade it just as well as my parents small 4x4 (geo tracker) but it wasn't a fun experience. 4x4 is just like any other prep gear, you buy it just in case but hope to never need it.

Practice as others said.

It is 250 miles from where we live to where we have out farm land and if we evac'ed that's where we could go. You need to drive to and from often, budget for a trip ever month or two. Make a stop at the local stores, people will start to recognize you. You need to start taking detours every now and then. We'll look for places off the main highway and take an exit somewhere before and after to detour and make a stop. This helps you get familiar with alternate routes.

The average car gets 300-400 miles on a tank, stop and go traffic will cut that down as will pulling trailers or strapping items to the roof, taking detours, backtracking, etc. You need to take that into account. If your evac is also 300-400 miles then you have to keep a full tank or enough extra to top it off before you leave and enough safely carried to extend that range.

CB radio or scanner helps to gather intel along the route, traffic jams, accidents, etc.