Sometimes when I see such black and white comments as "this caliber will stop any [bear/bad guy/sith lord]," I get a little worried. Nothing ever works 100% of the time. A fine defensive caliber like .357 has failed at times. A state trooper placed multiple rounds of .357 center mass on his assailant, but that didn't stop the bad guy, who survived. Unfortunately, the trooper did not. So before packing your favorite caliber for the extreme unlikely situation of encountering a grizzly intent on killing you, please remember that your mileage may vary.