I treat the weather seals on the doors of my vehicles with Silicon Spray about twice a year. This helps keep water from soaking into the foam rubber and freezing the doors shut. My fiance was having problems with frozen doors on her old Buick Century, and once I treated the door seals with Silicon Spray she hasn't had trouble since.

Teflon would probably work just as well. Make sure whatever you use dones't have any oil-bases solvents - Stick with pure Silicon Spray, or it could actually degrade the seals.