All batteries in every device need to be matched in chemistry, capacity and state of charge. If they are mismatched, alkalines are far more prone to leakage and lithiums can vent, possibly with flame. Devices that take only one battery don't have this problem, although alkalines will always leak eventually.

The easiest way is to put only new cells from the same package into a device, never reusing cells in devices that take more than one. I go a step further and use a pulse-load battery tester on CR123A batteries before installation.