The early episodes with Morgan seemed to indicate bugging in would work; maybe board up a couple windows & generally stay quiet and out of sight. The Vatos also seemed to make it work, though in a much more challenging environment (dense urban vs. suburban). And of course Hershel's clan was doing okay staying put too.

Keeping moving not only means you are constantly foraging for the essentials, running the risk of dehydration and malnutrition / starvation, but you are constantly vulnerable to the zombies because you don't have a permanent location that can be secured and made defensible.

Even with Romero, the majority of the characters in Dawn of the Dead died because they got bored hanging out in the mall and hit the road instead. And Night of the Living Dead would've been an incredibly boring (but relatively body count free) movie if they'd simply turned out all the lights and hid in the basement .