We're finally begining to get human research on BPA and health. There are hundreds of studies that mention its effects in the lab or in animal experiments but very little research results in people. But that situation is slowly changing.

This article mentions a 2010 paper that confirms the authors' earlier analysis that higher BPA is associated with higher risk of heart disease. In this case, 33% higher risk. And we're not talking about unrealistic amounts of BPA but levels that normal people have in their daily lives.

The actual mechanism between BPA and heart disease is still unknown, so we can't say with any certainty that the BPA is causing the higher risk of heart disease yet, but these two analyses in two different sets of human data is pretty convincing evidence to me that there is something "there" there and that it is not some theoretical possbility that requires "drinking acid out of the bottle 24/7".

I originally came out defending BPA in my posts when the controversey first started. But since then, I have been progressively swayed the other way as more and more data piles up indicating possible harmful effects. So I think it is totally reasonable for people to be concerned about long term exposure to BPA based on what is currently known.

The other problem with BPA is the current paradigm for determing the "safe" level of BPA (the same system that sets limits for things like mercury and lead) doesn't really work for hormone-disrupting substances like BPA where smaller doses can be more harmful than larger ones, so it's going to take a long time for that system to catch up and change with the latest research.