For a CERT call-out I'm good as long as I get the word at home; my CERT gear is by the door and fully packed. For a work-related call-out I might have to pack my laptop up but otherwise I'm ready.
For a bug out, if all we can grab on the way out the door is one of our BOBs, we're in pretty good shape. Mine is in my car and hers is in her van, at all times.
If there's time to load the rest of the bug-out/bug-in gear, it's containerized in wife-portable chunks. She can load it into the van by herself if I'm not home. One exception would be guns, which are always locked up when not on someone's person. Another exception is cash; finances have not permitted me to put together a useful amount to stash in the BOBs. I'd like to have enough on hand so that if cash still works but ATMs and credit cards don't we'd still be able to buy gas, food and lodging.
If there's a few minutes more, we start loading comfort items and the like. There's a checklist based loosely on Blast's Binder.