Yes.
I regularly hike, ski, road bike, trail run, snowshoe, mountain bike, flat water paddle, jeep and climb solo on trips ranging from a few hours to several days. I'd get out a lot less if I had to find a partner every time I felt like going outside. I've never had any serious problems in more than 20 years of solo activities. It could happen someday but that possibility isn't enough to keep me sitting inside or just doing "safe" things alone.