We have a 30' Born Free RV, which is one of more drivable of the RVs of that size. I find it usually has a 2:1 fatigue factor: I can go about half as far per day as I could driving a sedan (a truck driver or someone used to piloting a large sail on the highway wouldn't have a problem). On gusty days it is much worse.

One other thing: with most RV's you only roll them over once. After that, you're not rolling anything over again. The Born Free has roll bars which was a big plus for me when buying, but I'm not optimistic about survivability. *Any* towed scheme is safer.

The Born Free uses a Ford E450 platform. I think it's a much safer and sturdier platform than anything else until you get to a converted bus, but beware the weight capacity limits if you get a diesel engine.