I think about it as a scenario / layer / planning problem.

If anything happens that requires a response while I am on the move my EDC must get me to "somewhere". So If I am walking / riding the subway / flying / or in someone elses vehicle and I become stranded suddenly on-foot I need:

1) to be able to tend to minor to medium trauma (major trauma is considered fatal in this scenario),
2) ability to signal for rescue,
3) fire
4) shelter
5) water

If anything happens that requires a response while I am in my vehicle I will have my EDC and my auto kit all of the above needs apply with the addition of
6) minor to medium auto repair

there will be some redundancy between the EDC and the auto kit because I can carry larger items in the auto kit and there is real capacity for fuel, water, food - none of which is carried EDC in any large volume. There may be a power bar and a liter of water but that's it.

If anything happens to my work place I need to be able to upgrade my situation to a vehicle transport situation. The major supplies I store in the office are related to building evacuation and getting me to my vehicle (or my home). If I were to use transport other than my own vehicle to get to the office I would have to solve more tha building evac with my office kit. Also I consider anything larger than my EDC unlikely to get out of the building with me for many reasons. I might not be able to get back to my desk from the meeting after the event, there may be working security preventing me from evacuating with a large pack of supplies etc... So, for the workplace scenarios, I try to have my supplies for getting me home outside of the building and only have the building evac supplies on premises. This could be accomplished through a rented locker if you were truely urban situation or with an enhanced vehicle kit and a practice of parking a block or two away from the office instead of in the attached garage. In my case I can park in an open lot several hundred feet away from the 1 story structure which is my office building.

Office bob == building evac

1) smoke / dust / debris handling - gloves, mask, eye protection
2) fire protection / suppression
3) debris stabilization - rope, zip-ties, duct-tape
4) Extrication - prybar, etc
5) info / comms - am/fm/sw/wb radio, HAM radio, Cell phone

Near Office supplies (preferrably on in the office)
1) travel - Cab fare, bicycle, vehicle in different location, decent extra shoes,
See above EDC and auto kit for other travel supplies needed

Scenarios that arise at home can be handled similar to the office scenario. I keep my bob supplies outside of my home in the shed because if the house burns down and I am not able to reach my bob I don't want to be without it. If my shed burns down I still may have my house and not need my BOB. I do keep extrication tools and fire suppression tools handy in most likely areas withn the house. Extrication isn't too much of a concern since I can't afford that big a house but fire suppression is needed and available in the kitchen, rooms with fire-places / wood-stoves, basement utility room, laundry room, garage. Escape ladders are available in each of the bedrooms.

My BOB at home is predicated on an escape to safety scenario. I have destinations selected from next-door to across town to out of state where I can go safely in case I can't stay home. The BOB is sufficient to take me walking to those destinations I can walk to and when supplemented with the auto kit it will take me safely to the out-of-state locations. It includes a sturdy change of clothes for each family member, extra glasses, building extrication and stabilization supplies, trauma medical supplies, food and water, debris handling supplies (this is something I don't hear too much about but If I were to activate a bob-based evacuation in my vehicle I would always include a good shovel, the chain-saw and prybar, some stout planking (2X6 minimum) to clear debris from the road (downed trees), fill / bridge large pot-holes, some decent tow straping and a winch for vehicle extrication. Keeping the vehicle rolling is very important to the out-of-state evacuation.

OK so I've rambled on long enough. I hope you get the idea of my approach.

No, I wouldn't carry my BOB around with me and No I don't have the chainsaw packed in the BOB but I wouldn't leave home without it.

1) travel options - money, comms,