Short answer: Probably. Depends on the screener.

More complete answer: In well over 20 commercial flights, my keys with a res-q-me while riding in a laptop bag have never elicited a comment, even when the bag was being hand-searched. The bag normally doesn't get a second look which is interesting given all the stuff I carry.

Once, when I was still asleep (early flight), I tried to go through the metal detector with keys still in my pocket. I handed them over to the screener who examined the res-q-me carefully, asked me if the blade could be removed, tried to remove the blade, then took it back to his supervisor. I got the green light.