Some things I learned a long time ago in carrying heavy packs long distances-
If you carry it twice and don't use it, and it is not on the 10 essentials list - don't carry it again.
If you can find a lighter or smaller version of what you are carrying, and it will make you as happy as the original, get it.
Never carry a single use item. Multitask everything.
Never forget the toilet paper.
It's more a matter of what you can do with what you have than what you can do without.