Originally Posted By: bilojax
When the path is clear and those conditions are met, drive to the river with your boats and gear and launch. Travel to a pre-selected wilderness area, and start living the good life until society settles down.

Usually going downstream leads you towards more civilization, not away from it. I suppose with a power boat you could go upstream on large flat slow moving rivers, but those are probably heavily populated along their entire route - upstream and downstream. You might be able to follow a river into a swamp and find wilderness that way. Are there many boat-navigable rivers in the USA that lead into wilderness areas?