I have other water in the backpack, so it doesn't need to reside in the Nalgene bottle right now. The Nalgene bottle (and it's contents) are for a survival situation, so I'm not concerned about having to remove the stuff to use the bottle.
There's water everywhere here, I doubt I'd have a hard time sourcing any. And I bet my odds are better of winning the lottery every week for a year straight than of having an earthquake hit here.
I'm also not too worried about the stuff that I'm now carrying in the Nalgene bottle getting wet when I take it out. Most of it is a waterproof flashlight, a Fox 40 whistle, a knife sharpener, a magnesium fire starter, a wire saw, a Starflash signal mirror, a waterproof match safe, etc... I'm just trying to conserve space by not having to take up space in other parts of the bag. In my opinion, anything in my bag that can contain something inside of it, should do so to conserve space.