I had a bad experience taking OTC medication containing chlorpheniramine maleate. I had taken the daily dose for about a week when I started to not feel like my normal happy self. I became very moody and upset over the smallest problem, it did not help that I was doing a very difficult and boring job at the time. The day after I ran out of the medication it was like I was back to my old self, the world was a good place again.
I now take pseudoephedrine as a decongestant, and have no problems.
Mike