Clearwater, I think you're saying that keeping your wool socks from getting chewed up by rubbing against the boot is the primary reason for the thin, synthetic, outer layer, right? When I was younger and played a lot of soccer, I always wore synthetic socks. Not very comfortable, but I never managed to rub a hole through them, so I agree that synthetics can take a lot of abuse.

And the clamminess and odor issues would be the main reasons against wearing synthetic as the inner layer for you.